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Models of Distribution of Electric Field of Primary Cilia as Monopole Antennas

Received: 19 August 2018     Accepted: 11 October 2018     Published: 7 November 2018
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Abstract

Background: The primary cilium is a solitary, chemosensory and mechanosensory, non-motile microtubule-based organelle which in the quiescent cell cycle phase projects from the surface of most cells in vertebrates, including humans. A hypothesis has been proposed that the cell endogenous electromagnetic field results from a unique cooperating system among microtubules and mitochondria. The present study expands this prior hypothesis of the endogenous electromagnetic field in the cell to the present hypothesis that primary cilium could serve as a monopole antenna. It is proposed that primary cilia as monopole antennas can serve for both transmitting and receiving signals at the same frequency. Results: There was simulated the distribution of electric field of primary cilium as a monopole antenna of a single cell, primary cilia after mitosis and primary cilium of renal tubule in water environment. According to simulations of the distribution of electric field of primary cilium as a monopole antenna, the electromagnetic waves radiate not only to the neighbouring cells, but also to the nucleus of the cell proper where the gene expression during the cell cycle could be changed. Conclusions: The present study provides the first simulations of electromagnetic field of primary cilia as monopole antennas. The proof of this function of primary cilia could extend diagnostic and therapeutic modalities. There are several ways to verify this hypothesis. For example, it is possible to use the voltage sensitive dyes in the microenvironment outside the primary cilium or photon counting with low noise and highly sensitive photon counting system.

Published in Journal of Cancer Treatment and Research (Volume 6, Issue 3)
DOI 10.11648/j.jctr.20180603.11
Page(s) 37-43
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Primary Cilia, Monopole Antennas, Distribution of Electric Field Models

References
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Cite This Article
  • APA Style

    Josef Dvorak, Bohuslav Melichar, Alzbeta Filipova, Tomas Korinek, Nela Grimova, et al. (2018). Models of Distribution of Electric Field of Primary Cilia as Monopole Antennas. Journal of Cancer Treatment and Research, 6(3), 37-43. https://doi.org/10.11648/j.jctr.20180603.11

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    ACS Style

    Josef Dvorak; Bohuslav Melichar; Alzbeta Filipova; Tomas Korinek; Nela Grimova, et al. Models of Distribution of Electric Field of Primary Cilia as Monopole Antennas. J. Cancer Treat. Res. 2018, 6(3), 37-43. doi: 10.11648/j.jctr.20180603.11

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    AMA Style

    Josef Dvorak, Bohuslav Melichar, Alzbeta Filipova, Tomas Korinek, Nela Grimova, et al. Models of Distribution of Electric Field of Primary Cilia as Monopole Antennas. J Cancer Treat Res. 2018;6(3):37-43. doi: 10.11648/j.jctr.20180603.11

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  • @article{10.11648/j.jctr.20180603.11,
      author = {Josef Dvorak and Bohuslav Melichar and Alzbeta Filipova and Tomas Korinek and Nela Grimova and Jana Grimova and Aneta Rozsypalova and Jan Proks and Tomas Buchler and Igor Richter},
      title = {Models of Distribution of Electric Field of Primary Cilia as Monopole Antennas},
      journal = {Journal of Cancer Treatment and Research},
      volume = {6},
      number = {3},
      pages = {37-43},
      doi = {10.11648/j.jctr.20180603.11},
      url = {https://doi.org/10.11648/j.jctr.20180603.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20180603.11},
      abstract = {Background: The primary cilium is a solitary, chemosensory and mechanosensory, non-motile microtubule-based organelle which in the quiescent cell cycle phase projects from the surface of most cells in vertebrates, including humans. A hypothesis has been proposed that the cell endogenous electromagnetic field results from a unique cooperating system among microtubules and mitochondria. The present study expands this prior hypothesis of the endogenous electromagnetic field in the cell to the present hypothesis that primary cilium could serve as a monopole antenna. It is proposed that primary cilia as monopole antennas can serve for both transmitting and receiving signals at the same frequency. Results: There was simulated the distribution of electric field of primary cilium as a monopole antenna of a single cell, primary cilia after mitosis and primary cilium of renal tubule in water environment. According to simulations of the distribution of electric field of primary cilium as a monopole antenna, the electromagnetic waves radiate not only to the neighbouring cells, but also to the nucleus of the cell proper where the gene expression during the cell cycle could be changed. Conclusions: The present study provides the first simulations of electromagnetic field of primary cilia as monopole antennas. The proof of this function of primary cilia could extend diagnostic and therapeutic modalities. There are several ways to verify this hypothesis. For example, it is possible to use the voltage sensitive dyes in the microenvironment outside the primary cilium or photon counting with low noise and highly sensitive photon counting system.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Models of Distribution of Electric Field of Primary Cilia as Monopole Antennas
    AU  - Josef Dvorak
    AU  - Bohuslav Melichar
    AU  - Alzbeta Filipova
    AU  - Tomas Korinek
    AU  - Nela Grimova
    AU  - Jana Grimova
    AU  - Aneta Rozsypalova
    AU  - Jan Proks
    AU  - Tomas Buchler
    AU  - Igor Richter
    Y1  - 2018/11/07
    PY  - 2018
    N1  - https://doi.org/10.11648/j.jctr.20180603.11
    DO  - 10.11648/j.jctr.20180603.11
    T2  - Journal of Cancer Treatment and Research
    JF  - Journal of Cancer Treatment and Research
    JO  - Journal of Cancer Treatment and Research
    SP  - 37
    EP  - 43
    PB  - Science Publishing Group
    SN  - 2376-7790
    UR  - https://doi.org/10.11648/j.jctr.20180603.11
    AB  - Background: The primary cilium is a solitary, chemosensory and mechanosensory, non-motile microtubule-based organelle which in the quiescent cell cycle phase projects from the surface of most cells in vertebrates, including humans. A hypothesis has been proposed that the cell endogenous electromagnetic field results from a unique cooperating system among microtubules and mitochondria. The present study expands this prior hypothesis of the endogenous electromagnetic field in the cell to the present hypothesis that primary cilium could serve as a monopole antenna. It is proposed that primary cilia as monopole antennas can serve for both transmitting and receiving signals at the same frequency. Results: There was simulated the distribution of electric field of primary cilium as a monopole antenna of a single cell, primary cilia after mitosis and primary cilium of renal tubule in water environment. According to simulations of the distribution of electric field of primary cilium as a monopole antenna, the electromagnetic waves radiate not only to the neighbouring cells, but also to the nucleus of the cell proper where the gene expression during the cell cycle could be changed. Conclusions: The present study provides the first simulations of electromagnetic field of primary cilia as monopole antennas. The proof of this function of primary cilia could extend diagnostic and therapeutic modalities. There are several ways to verify this hypothesis. For example, it is possible to use the voltage sensitive dyes in the microenvironment outside the primary cilium or photon counting with low noise and highly sensitive photon counting system.
    VL  - 6
    IS  - 3
    ER  - 

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Author Information
  • Department of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic

  • Department of Oncology, Palacky University Medical School and Teaching Hospital, Olomouc, Czech Republic

  • Department of Radiobiology, Faculty of Military Health Sciences in Hradec Kralove, University of Defense in Brno, Hradec Kralove, Czech Republic

  • Department of Electromagnetic Field, Faculty of Electrical Engineering, Czech Technical University, Prague, Czech Republic

  • Department of Cybernetics, Faculty of Electrical Engineering, Czech Technical University, Prague, Czech Republic

  • Medicon, Prague, Czech Republic

  • Department of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic

  • Department of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic

  • Department of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic

  • Department of Oncology, Regional Hospital, Liberec, Czech Republic

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