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Predictors of Mortality of Oncological Patients Admitted in the Pediatric ICU of a Tertiary Reference Hospital

Received: 2 June 2021     Accepted: 22 June 2021     Published: 9 July 2021
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Abstract

Cancer in the childhood and adolescence age group is considered rare. Despite this, the incidence of new diagnoses is increasing every day, as well as an increase in the cure rate, which is due, among other reasons, to the intensification of cancer treatment. As a consequence, these patients end up needing intervention in intensive care units (ICU). When compared to other patients, the mortality rate of cancer patients was higher than the general mortality in the pediatric ICU. For this reason, it is important to identify prognostic factors that can guide the early admission of these patients to the ICU. This study evaluated several variables related to the cancer patient admitted to the ICU, correlating them with the clinical outcome. Some variables were identified that increased the risk of the patient presenting with death as outcome, namely the number of organic dysfunctions on admission, the use of cardiotoxic chemotherapy, the use of nephrotoxic medications and the number of interventions performed on the patient in the first hours in the ICU. It is hoped that with this article, teams that provide health care to pediatric cancer patients will be able to identify children and adolescents in need of ICU interventions earlier, thus increasing their survival rate.

Published in Journal of Cancer Treatment and Research (Volume 9, Issue 3)
DOI 10.11648/j.jctr.20210903.11
Page(s) 45-49
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Pediatric Oncology, Pediatric ICU, Organic Dysfunctions, Cardiotoxic Chemotherapy, Nephrotoxic Medications

References
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[5] Ali, A. M; Sayed, H. A; Elzembely, M. M.; The Outcome of Critically Ill Pediatric Cancer Patients Admitted to the Pediatric Intensive Care Unit in a Tertiary University Oncology Center in a Developing Country: A 5-Year Experience. J Pediatric Haemotol Oncol, 38: 355-359, 2016.
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  • APA Style

    Ynnaiana Navarro De Lima Santana Quintans, Denise Bousfield Da Silva, Nilzete Liberato Bresolin, Joana Sacheti Freitas. (2021). Predictors of Mortality of Oncological Patients Admitted in the Pediatric ICU of a Tertiary Reference Hospital. Journal of Cancer Treatment and Research, 9(3), 45-49. https://doi.org/10.11648/j.jctr.20210903.11

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    ACS Style

    Ynnaiana Navarro De Lima Santana Quintans; Denise Bousfield Da Silva; Nilzete Liberato Bresolin; Joana Sacheti Freitas. Predictors of Mortality of Oncological Patients Admitted in the Pediatric ICU of a Tertiary Reference Hospital. J. Cancer Treat. Res. 2021, 9(3), 45-49. doi: 10.11648/j.jctr.20210903.11

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    AMA Style

    Ynnaiana Navarro De Lima Santana Quintans, Denise Bousfield Da Silva, Nilzete Liberato Bresolin, Joana Sacheti Freitas. Predictors of Mortality of Oncological Patients Admitted in the Pediatric ICU of a Tertiary Reference Hospital. J Cancer Treat Res. 2021;9(3):45-49. doi: 10.11648/j.jctr.20210903.11

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  • @article{10.11648/j.jctr.20210903.11,
      author = {Ynnaiana Navarro De Lima Santana Quintans and Denise Bousfield Da Silva and Nilzete Liberato Bresolin and Joana Sacheti Freitas},
      title = {Predictors of Mortality of Oncological Patients Admitted in the Pediatric ICU of a Tertiary Reference Hospital},
      journal = {Journal of Cancer Treatment and Research},
      volume = {9},
      number = {3},
      pages = {45-49},
      doi = {10.11648/j.jctr.20210903.11},
      url = {https://doi.org/10.11648/j.jctr.20210903.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20210903.11},
      abstract = {Cancer in the childhood and adolescence age group is considered rare. Despite this, the incidence of new diagnoses is increasing every day, as well as an increase in the cure rate, which is due, among other reasons, to the intensification of cancer treatment. As a consequence, these patients end up needing intervention in intensive care units (ICU). When compared to other patients, the mortality rate of cancer patients was higher than the general mortality in the pediatric ICU. For this reason, it is important to identify prognostic factors that can guide the early admission of these patients to the ICU. This study evaluated several variables related to the cancer patient admitted to the ICU, correlating them with the clinical outcome. Some variables were identified that increased the risk of the patient presenting with death as outcome, namely the number of organic dysfunctions on admission, the use of cardiotoxic chemotherapy, the use of nephrotoxic medications and the number of interventions performed on the patient in the first hours in the ICU. It is hoped that with this article, teams that provide health care to pediatric cancer patients will be able to identify children and adolescents in need of ICU interventions earlier, thus increasing their survival rate.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Predictors of Mortality of Oncological Patients Admitted in the Pediatric ICU of a Tertiary Reference Hospital
    AU  - Ynnaiana Navarro De Lima Santana Quintans
    AU  - Denise Bousfield Da Silva
    AU  - Nilzete Liberato Bresolin
    AU  - Joana Sacheti Freitas
    Y1  - 2021/07/09
    PY  - 2021
    N1  - https://doi.org/10.11648/j.jctr.20210903.11
    DO  - 10.11648/j.jctr.20210903.11
    T2  - Journal of Cancer Treatment and Research
    JF  - Journal of Cancer Treatment and Research
    JO  - Journal of Cancer Treatment and Research
    SP  - 45
    EP  - 49
    PB  - Science Publishing Group
    SN  - 2376-7790
    UR  - https://doi.org/10.11648/j.jctr.20210903.11
    AB  - Cancer in the childhood and adolescence age group is considered rare. Despite this, the incidence of new diagnoses is increasing every day, as well as an increase in the cure rate, which is due, among other reasons, to the intensification of cancer treatment. As a consequence, these patients end up needing intervention in intensive care units (ICU). When compared to other patients, the mortality rate of cancer patients was higher than the general mortality in the pediatric ICU. For this reason, it is important to identify prognostic factors that can guide the early admission of these patients to the ICU. This study evaluated several variables related to the cancer patient admitted to the ICU, correlating them with the clinical outcome. Some variables were identified that increased the risk of the patient presenting with death as outcome, namely the number of organic dysfunctions on admission, the use of cardiotoxic chemotherapy, the use of nephrotoxic medications and the number of interventions performed on the patient in the first hours in the ICU. It is hoped that with this article, teams that provide health care to pediatric cancer patients will be able to identify children and adolescents in need of ICU interventions earlier, thus increasing their survival rate.
    VL  - 9
    IS  - 3
    ER  - 

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Author Information
  • Department of Pediatric Oncology and Hematology, Joana de Gusm?o Children's Hospital, Florianópolis, Brazil

  • Department of Pediatric Oncology and Hematology, Joana de Gusm?o Children's Hospital, Florianópolis, Brazil

  • Department of Pediatric Nephrology, Joana de Gusm?o Children's Hospital, Florianópolis, Brazil

  • Department of Pediatric Oncology and Hematology, Joana de Gusm?o Children's Hospital, Florianópolis, Brazil

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