| Peer-Reviewed

Factors of Local Recurrence in Soft Tissue Sarcomas at Yalgado Ouédraogo University Hospital (Burkina Faso)

Received: 23 June 2017     Accepted: 5 July 2017     Published: 2 August 2017
Views:       Downloads:
Abstract

Soft tissue sarcomas are characterized by their great anatomo-clinical diversity and their high potential for recurrence. Our Objective was to determine recurrence factors in soft tissue sarcomas in the General and Digestive Surgery Unit of Yalgado Ouédraogo University Hospital from 1st January 2010 to 30th August 2015. This is a cohort retrospective study which concerns patients followed-up for soft tissue sarcomas in the General and Digestive Surgery Unit of Yalgado Ouédraogo University Hospital from 1st January 2010 to 30th August 2015. The data were analyzed with Epi-info 7 software. To assess the stability of associations, Pearson’s chi square tests or Fisher exact tests were used. A risk α=0.05 was admitted. Fifty-four cases of soft tissue sarcomas were collected and 40 cases included in the study. The frequency of soft tissue sarcomas was 0.03% compared to all cancers in our department. On univariate analysis, recurrences were significantly associated with the tumour resection margin (p=0.014), the operator’s qualification (p=0.012), the histologic type (p=0.04) and the recurrence history (p=0.0004). On multivariate analysis, the resection margin remained significantly associated with recurrences (p=0.03). Recurrence factors mostly involved the resection margin, the operator’s qualification, the histologic type and the recurrence history. A good mastery of soft tissue sarcomas surgery will significantly reduce recurrence risks.

Published in Journal of Cancer Treatment and Research (Volume 5, Issue 4)
DOI 10.11648/j.jctr.20170504.12
Page(s) 66-70
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Sarcomas, Soft Tissue, Recurrence, Ouagadougou

References
[1] Bonvalot S, Vanel D, Terrier P, Le Pechaux C, Lecesne A. Principles for the treatment of soft tissue sarcoma in adults. EMC-Rhumatologie Orthopédie. 2004; 1: 521-541.
[2] Kasse AA, Diop M, Dieng M, Deme A, Fall MC, Diop P, Betel E, Drabo B, Timbely G, Touré P. Les facteurs de récidive des sarcomes des parties molles: étude d’une série rétrospective de 125 cas. e-mémoires de l’Académie Nationale de Chirurgie. 2003; 2: 30-34.
[3] Bonvalot S, Missana M, Le CesneM, Missenard G, Vanel D, Terrier P. Chirurgie des sarcomes des tissus mous des membres chez l’adulte historique et avancées thérapeutiques Cancer/Radiothérapie. 2006; 10: 416-424.
[4] Moureau-Zabatta L, Thomas L, Bui B, Cheveau C, Stockle E, Martel P, Bonneviale P, Marques B. Prise en charge des sarcomes des tissus mou en première rechute locale isolée: étude rétrospective de 83 cas. cancer / radiothérapie. 2004; 8: 279-287.
[5] Lintz F, Moreau A, Cassagneau E, Maillard O, Waast D, Couin F. Sarcome des tissus mous: étude des marges de résection. Orthopaedics & Traumatology: Surgery & Research. 2012; 98: 9-18.
[6] Bonvalot S, Stockle E, Cuisenier J, Depadt G, Goin J, Lorimier G. Nouvelles techniques chirurgicales des sarcomes des tissus mous. EMC-Rhumatologie Orthopédie. 2004; 1: 521-541.
[7] Penel N, Lartigau E, Fournier C, Vilain M. Sarcomes des tissus mous thoraciques de l’adulte: étude rétrospective de 40 cas. Ann chir. 2003; 128: 237-245.
[8] Bonvalot S, Kolb F, Mamlouk K, Cavalcavite A, LePechaux C. Reconstruction par lambeau libres dans les sarcomes localement évolués. Ann Chir. 2001; 126: 30-83.
[9] Stefanovski P, Bidoli E, De Paoli A, Buonadonna A, Boz G, Libra M, Morassut S, Rossi C, Carbone A, Frustaci S. Prognostic factors in soft tissue sarcomas: a study of 395 patients. EJSO. 2002; 28: 153-164.
[10] Honoré C, Méeus P, Stoeckle E, Bonvalot S. Soft tissue sarcoma in France in 2015: Epidemiology, classification andorganization of clinical care. Journal of Visceral Surgery. 2015; 489: 8.
[11] Atean I, Pointreau Y, Rosset P, Garaud P, De-Pinieux G, Calais G. Prognostic factors of extremity soft tissue sarcoma in adults: A single institutional analysis. Cancer/Radiothérapie. 2012; 16: 661-666.
[12] Heymanna S, Junga G, Simonb P, Bergeratb J, Borela C, Di Marcob A. Résultats à long terme d’une série de 89 patients suivis pour un sarcome des tissus mous traités par chirurgie conservatrice et trois modalités d’irradiation postopératoire. Cancer/Radiothérapie. 2007; 11: 443-451.
[13] Fletcher M, Unni K, Mertens F. World Health Organization Classification of Tumors. Pathology and genetics of tumors of soft tissue and bone. Lyon: IARC Press, 2002.
[14] Mandong B, Kidmas T, Manassé N, Echejoh O, TankoN, Madaki J. Épidémiologie sarcomes des tissus mous à Jos, Centre Nord du Nigeria. Niger J Med. Juil. 2007; 16: 246.
[15] El ouni F, Jemni H, Trabelsi A et al. Liposarcomes des membres: caractéristiques présentes en IRM et leur corrélation avec l’histopathologie. Révue de chirurgie orthopédique et traumatologique. 2010; 96: 970-977.
[16] Quynh-thu L, Karen K, Stew K, Linda F, Vincent M. Prognostic factors in adult soft-tissue sarcomas of the head and neck. Radiation Oncology Biol. Phys. 1997; 37: 975-984.
[17] Takashi Y, Kenichi S. Risk factor of lymphatic metastasis of malignant bone and soft tissue tumors A retrospective cohort study of 242 patients. Md-journal 2014, 93: 27.
[18] Mc gee L, Daniel J, Indeliceto M, Roi Dagan M. Long-term results following postoperative radiothérapy of soft tissue sarcomas of extremity. Int. J radiation oncol 2012; 84: 1003-1009.
[19] Amadeo B, Delafosse P et al. Survie des personnes atteintes de cancer en France métropolitaine 1989-2013 partie 1 tumeurs solides.
Cite This Article
  • APA Style

    Zongo Nayi, Doamba Rodrigue, Ollo Roland Somé, Ouédraogo Smaïla, Korsaga-Somé Nina, et al. (2017). Factors of Local Recurrence in Soft Tissue Sarcomas at Yalgado Ouédraogo University Hospital (Burkina Faso). Journal of Cancer Treatment and Research, 5(4), 66-70. https://doi.org/10.11648/j.jctr.20170504.12

    Copy | Download

    ACS Style

    Zongo Nayi; Doamba Rodrigue; Ollo Roland Somé; Ouédraogo Smaïla; Korsaga-Somé Nina, et al. Factors of Local Recurrence in Soft Tissue Sarcomas at Yalgado Ouédraogo University Hospital (Burkina Faso). J. Cancer Treat. Res. 2017, 5(4), 66-70. doi: 10.11648/j.jctr.20170504.12

    Copy | Download

    AMA Style

    Zongo Nayi, Doamba Rodrigue, Ollo Roland Somé, Ouédraogo Smaïla, Korsaga-Somé Nina, et al. Factors of Local Recurrence in Soft Tissue Sarcomas at Yalgado Ouédraogo University Hospital (Burkina Faso). J Cancer Treat Res. 2017;5(4):66-70. doi: 10.11648/j.jctr.20170504.12

    Copy | Download

  • @article{10.11648/j.jctr.20170504.12,
      author = {Zongo Nayi and Doamba Rodrigue and Ollo Roland Somé and Ouédraogo Smaïla and Korsaga-Somé Nina and Ouangré Edgar and Zida Maurice and Bonkoungou Gilbert and Ouédraogo Aimé Sosthène and Bambara Aboubacar Hirrum and Bambara Augustin Tozoula and Traoré Si Simon and Niamba Pascal and Traoré Adama and Gilbert Bonkoungou and Sanou Adama and Dem Ahmadou},
      title = {Factors of Local Recurrence in Soft Tissue Sarcomas at Yalgado Ouédraogo University Hospital (Burkina Faso)},
      journal = {Journal of Cancer Treatment and Research},
      volume = {5},
      number = {4},
      pages = {66-70},
      doi = {10.11648/j.jctr.20170504.12},
      url = {https://doi.org/10.11648/j.jctr.20170504.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20170504.12},
      abstract = {Soft tissue sarcomas are characterized by their great anatomo-clinical diversity and their high potential for recurrence. Our Objective was to determine recurrence factors in soft tissue sarcomas in the General and Digestive Surgery Unit of Yalgado Ouédraogo University Hospital from 1st January 2010 to 30th August 2015. This is a cohort retrospective study which concerns patients followed-up for soft tissue sarcomas in the General and Digestive Surgery Unit of Yalgado Ouédraogo University Hospital from 1st January 2010 to 30th August 2015. The data were analyzed with Epi-info 7 software. To assess the stability of associations, Pearson’s chi square tests or Fisher exact tests were used. A risk α=0.05 was admitted. Fifty-four cases of soft tissue sarcomas were collected and 40 cases included in the study. The frequency of soft tissue sarcomas was 0.03% compared to all cancers in our department. On univariate analysis, recurrences were significantly associated with the tumour resection margin (p=0.014), the operator’s qualification (p=0.012), the histologic type (p=0.04) and the recurrence history (p=0.0004). On multivariate analysis, the resection margin remained significantly associated with recurrences (p=0.03). Recurrence factors mostly involved the resection margin, the operator’s qualification, the histologic type and the recurrence history. A good mastery of soft tissue sarcomas surgery will significantly reduce recurrence risks.},
     year = {2017}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Factors of Local Recurrence in Soft Tissue Sarcomas at Yalgado Ouédraogo University Hospital (Burkina Faso)
    AU  - Zongo Nayi
    AU  - Doamba Rodrigue
    AU  - Ollo Roland Somé
    AU  - Ouédraogo Smaïla
    AU  - Korsaga-Somé Nina
    AU  - Ouangré Edgar
    AU  - Zida Maurice
    AU  - Bonkoungou Gilbert
    AU  - Ouédraogo Aimé Sosthène
    AU  - Bambara Aboubacar Hirrum
    AU  - Bambara Augustin Tozoula
    AU  - Traoré Si Simon
    AU  - Niamba Pascal
    AU  - Traoré Adama
    AU  - Gilbert Bonkoungou
    AU  - Sanou Adama
    AU  - Dem Ahmadou
    Y1  - 2017/08/02
    PY  - 2017
    N1  - https://doi.org/10.11648/j.jctr.20170504.12
    DO  - 10.11648/j.jctr.20170504.12
    T2  - Journal of Cancer Treatment and Research
    JF  - Journal of Cancer Treatment and Research
    JO  - Journal of Cancer Treatment and Research
    SP  - 66
    EP  - 70
    PB  - Science Publishing Group
    SN  - 2376-7790
    UR  - https://doi.org/10.11648/j.jctr.20170504.12
    AB  - Soft tissue sarcomas are characterized by their great anatomo-clinical diversity and their high potential for recurrence. Our Objective was to determine recurrence factors in soft tissue sarcomas in the General and Digestive Surgery Unit of Yalgado Ouédraogo University Hospital from 1st January 2010 to 30th August 2015. This is a cohort retrospective study which concerns patients followed-up for soft tissue sarcomas in the General and Digestive Surgery Unit of Yalgado Ouédraogo University Hospital from 1st January 2010 to 30th August 2015. The data were analyzed with Epi-info 7 software. To assess the stability of associations, Pearson’s chi square tests or Fisher exact tests were used. A risk α=0.05 was admitted. Fifty-four cases of soft tissue sarcomas were collected and 40 cases included in the study. The frequency of soft tissue sarcomas was 0.03% compared to all cancers in our department. On univariate analysis, recurrences were significantly associated with the tumour resection margin (p=0.014), the operator’s qualification (p=0.012), the histologic type (p=0.04) and the recurrence history (p=0.0004). On multivariate analysis, the resection margin remained significantly associated with recurrences (p=0.03). Recurrence factors mostly involved the resection margin, the operator’s qualification, the histologic type and the recurrence history. A good mastery of soft tissue sarcomas surgery will significantly reduce recurrence risks.
    VL  - 5
    IS  - 4
    ER  - 

    Copy | Download

Author Information
  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of Dermatology and Venerology, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of Pathologic Anatomy, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of Dermatology and Venerology, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of Dermatology and Venerology, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Division of General Surgery, University of Ouagadougou, Ouagadougou, Burkina Faso

  • Oncology Institute Joliot Curie of Dakar, University Cheick Anta Diop of Dakar, Dakar, Senegal

  • Sections