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Sinonasal Alveolar Rhabdomyosarcoma in an Adult Patient: A Case Report and Review of the Literature

Received: 12 December 2016     Accepted: 27 December 2016     Published: 20 March 2017
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Abstract

We report on a patient who presented to the ENT service with right side nasal obstruction. Imaging studies revealed an aggressive non-calcified solid heterogeneous mass centered in the right naso ethmoidal region. The mass was hyper enhanced following contrast media administration. The patient underwent partial tumor resection and a biopsy was performed confirming the presence of Solid Alveolar Rhabdomyosarcoma. The patient was treated with chemo-radiation therapy.

Published in Journal of Cancer Treatment and Research (Volume 5, Issue 2)
DOI 10.11648/j.jctr.20170502.12
Page(s) 11-14
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

CT, MRI, Ethmoidal, Rhabdomyosarcoma, Radio-Chemo Therapy

References
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[2] Taketoshi Yasuda, Kyle D. Perry, Marilu Nelson, et al. Alveolar rhabdomyosarcoma of the head and neck region in older adults: genetic characterization and a review of the literature. Hum Pathol. 2009; 40 (3): 341–348.
[3] V. Goosens, I. Van den Berghe, C. De Clercq, J. Casselman. Radiation-induced mandibular adult spindle cell rhabdomyosarcoma. International Journal of Oral and Maxillofacial Surgery. 2008; 37 (4): 395–397.
[4] Beatrice Mª J. Neves, Paulo A. de L. Pontes, Eliana M. Caran, Claudia Figueiredo, Luc L. M. Weckx, Reginaldo R. Fujita. Head and neck rhabdomyosarcoma in childhood. Brazilian Journal of Otorhinolaryngology. 2003; 69: 24-27.
[5] Smith IM, Anderson PJ, Yuen T, Tan E, David DJ. Rhabdomyosarcoma of the mandible e long term management from childhood to adulthood. J Plast Reconstr Aesthet Surg. 2008; 61 (5): 582-5.
[6] O. A. Fatusi, S. O. Ajike, S. O. Olateju, A. T. Adebayo, O. O. Gbolahan, S. A. Ogunmuyiwa. Clinico-epidemiological analysis of orofacial rhabdomyosarcoma in a Nigerian population”. Int J Oral Maxillofac Surg. 2009; 38 (3): 256-60.
[7] Shin Kariya, Patricia A. Schachern, Sebahattin Cureoglu, Michael M. Paparella, Kazunori Nishizaki. Histopathological temporal bone study of the metastatic rhabdomyosarcoma”. Auris Nasus Larynx. 2009; 36 (2): 221-223.
[8] Geok-Chin Tan, Mohd-Sidik Shiran, Abdul-Rahman Hayati, Noor-Akmal Sharifah, Mohammad Rohaizak, Aida-Selamat Nurul. Alveolar Rhabdomyosarcoma of the Left Hand with Bilateral Breast Metastases in an Adolescent Female. Journal of the Chinese Medical Association 2008; 71 (12): 639-642.
[9] Rolf Sjuve Scott, Jaishree Jagirdar. Right atrial botryoid rhabdomyosarcoma in an adult patient with recurrent pleomorphic rhabdomyosarcomas following doxorubicin therapy. Annals of Diagnostic Pathology. 2007; 11 (4): 274-6.
[10] Daniela Dalfior, Albino Eccher, Stefano Gobbo, et al. Primary pleomorphic rhabdomyosarcoma of the kidney in an adult. Annals of Diagnostic Pathology. 2008; 12 (4): 301-303.
[11] Melanie Duval, Ricardo Faingold, Anne-Sophie Carret, Sam J. Daniel. Nasal ala rhabdomyosarcoma misdiagnosed as a facial infection. International Journal of Pediatric Otorhinolaryngology Extra. 2008; 3 (1): 44-47.
[12] Elizabeth Charytonowicz, Carlos Cordon-Cardo, Igor Matushansky, Mel Ziman. Alveolar rhabdomyosarcoma: Is the cell of origin a mesenchymal stem cell?” Cancer Letters. 2009; 279 (2): 126-136.
[13] Minoru Kuroiwa, Jun Sakamoto, Akira Shimada, et al. Manifestation of alveolar rhabdomyosarcoma as primary cutaneous lesions in a neonate with Beckwith-Wiedemann syndrome. Journal of Pediatric Surgery; 2009; 44 (3): 31-5.
[14] Janez Lamovec, Metka Volavšek. Sclerosing rhabdomyosarcoma of the parotid gland in an adult: case report and review of the literature. Ann Diagn Pathol. 2009; 13 (5): 334-8.
[15] Cynthia Leaphart, David Rodeberg. Pediatric surgical oncology: Management of rhabdomyosarcoma. Surgical Oncology; 2007; 16 (3): 173-85.
[16] Sharad Chawla, Heather Tapp, Mark Schembri. Para-meningeal rhabdomyosarcoma with critical airway compromise: Role of endoscopic debulking surgery. International Journal of Pediatric Otorhinolaryngology Extra. 2007; 2 (4): 243-24.
Cite This Article
  • APA Style

    Ilson Sepulveda, Paulo Vera, Enrique Platin, M. Loreto Spencer, Vanessa Klaassen, et al. (2017). Sinonasal Alveolar Rhabdomyosarcoma in an Adult Patient: A Case Report and Review of the Literature. Journal of Cancer Treatment and Research, 5(2), 11-14. https://doi.org/10.11648/j.jctr.20170502.12

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    ACS Style

    Ilson Sepulveda; Paulo Vera; Enrique Platin; M. Loreto Spencer; Vanessa Klaassen, et al. Sinonasal Alveolar Rhabdomyosarcoma in an Adult Patient: A Case Report and Review of the Literature. J. Cancer Treat. Res. 2017, 5(2), 11-14. doi: 10.11648/j.jctr.20170502.12

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    AMA Style

    Ilson Sepulveda, Paulo Vera, Enrique Platin, M. Loreto Spencer, Vanessa Klaassen, et al. Sinonasal Alveolar Rhabdomyosarcoma in an Adult Patient: A Case Report and Review of the Literature. J Cancer Treat Res. 2017;5(2):11-14. doi: 10.11648/j.jctr.20170502.12

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  • @article{10.11648/j.jctr.20170502.12,
      author = {Ilson Sepulveda and Paulo Vera and Enrique Platin and M. Loreto Spencer and Vanessa Klaassen and Cristina Hidalgo and Rodrigo Ascui and Joaquín Ulloa},
      title = {Sinonasal Alveolar Rhabdomyosarcoma in an Adult Patient: A Case Report and Review of the Literature},
      journal = {Journal of Cancer Treatment and Research},
      volume = {5},
      number = {2},
      pages = {11-14},
      doi = {10.11648/j.jctr.20170502.12},
      url = {https://doi.org/10.11648/j.jctr.20170502.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20170502.12},
      abstract = {We report on a patient who presented to the ENT service with right side nasal obstruction. Imaging studies revealed an aggressive non-calcified solid heterogeneous mass centered in the right naso ethmoidal region. The mass was hyper enhanced following contrast media administration. The patient underwent partial tumor resection and a biopsy was performed confirming the presence of Solid Alveolar Rhabdomyosarcoma. The patient was treated with chemo-radiation therapy.},
     year = {2017}
    }
    

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    AU  - Ilson Sepulveda
    AU  - Paulo Vera
    AU  - Enrique Platin
    AU  - M. Loreto Spencer
    AU  - Vanessa Klaassen
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    T2  - Journal of Cancer Treatment and Research
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    JO  - Journal of Cancer Treatment and Research
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    AB  - We report on a patient who presented to the ENT service with right side nasal obstruction. Imaging studies revealed an aggressive non-calcified solid heterogeneous mass centered in the right naso ethmoidal region. The mass was hyper enhanced following contrast media administration. The patient underwent partial tumor resection and a biopsy was performed confirming the presence of Solid Alveolar Rhabdomyosarcoma. The patient was treated with chemo-radiation therapy.
    VL  - 5
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Author Information
  • Radiology Department, ENT-Head and Neck Surgery Service, General Hospital of Concepcion, Concepción, Chile

  • Radiotherapy Department, Oncology Service, General Hospital of Concepcion, Concepción, Chile

  • Oral and Maxillofacial Radiology Department, University of North Carolina School of Dentistry, Chapel Hill, NC, USA

  • Pathology Department, General Hospital of Concepción, Concepción, Chile

  • Pathology Department, General Hospital of Concepción, Concepción, Chile

  • Ophthalmology Service, General Hospital of Concepción, Concepción, Chile

  • Oncology Service, General Hospital of Concepcion, Concepción, Chile

  • ENT-Head and Neck Surgery Service, General Hospital of Concepcion, Concepción, Chile

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